Tanshinones are a class of chemical compounds. Examples include dihydrotanshinone, tanshinone I, or tanshinone IIA. These compounds are all naturally occurring and can all be isolated from Salvia miltiorrhiza. Dihydrotanshinone I has been reported to have cytotoxicity to a variety of tumor cells. Webtanshinone VI could efficiently affect the phosphorylation of Ser68 and Ser63. Moreover, in harsh conditions, the tanshinone VI could simultaneously restrain the expression of ERK 1/2 and increase the expression of phosphory-lated Survivin. As a result, in the oxygen deprivation and glucose deprivation conditions, tanshinone VI is not only
(PDF) Inhibition of bone resorption by Tanshinone VI …
WebFeb 12, 2008 · Effects of tanshinone VI, a diterpene from Tan-Shen, on humoral factor-induced phosphorylation of ERK and Akt during hypertrophy of cardiomyocytes and fibrosis of cardiac fibroblasts isolated from neonatal rats were examined. Treatment of cultured cardiomyocytes with 10 nM insulin-like growth factor-1 (IGF-1) or 10 nM endothelin-1 … WebThe possible effects of tanshinone VI (tsh), a diterpene from the root of Tan-Shen (Salvia miltiorrhiza, Bunge (Labiatae)) on hypertrophy and fibrosis in cultured neonatal rat cardiac … targhee lambson
Effects of tanshinone VI on phosphorylation of ERK and …
WebThe possible effects of tanshinone VI (tsh), a diterpene from the root of Tan-Shen (Salvia miltiorrhiza, Bunge (Labiatae)) on hypertrophy and fibrosis in cultured neonatal rat cardiac myocytes and fibroblasts were examined. Tsh had no significant effect on protein synthesis, which was evaluated by [ … WebTanshinone VI, extracted from the root of S. miltiorrhiza, which could greatly inhibit osteoclast differentiation and bone resorption by disrupting the formation of actin ring. Tanshinone VI... WebApr 30, 2024 · Role of miR-145 in the effect of Tanshinone II A on HeLa cells (A) qPCR analyses of the relative mRNA levels of miR-145 on HeLa cells at different concentrations (0, 2, 4, 8 μm). Gene expression was normalized to U6 mRNA level. ... Polyphyllin VI induces caspase-1-mediated pyroptosis via the induction of ROS/NF-κB/NLRP3/GSDMD signal axis … targhee lll