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WebFactor H autoantibodies have been associated with DDD (Meri, et al., 1992). In patients with DDD, these autoantibodies bind to and block the N-terminal region of the Factor H protein, which compromises its fluid-phase regulatory function. Atypical Hemolytic-Uremic Syndrome. Factor H autoantibodies are identified in ~10% patients with aHUS ... WebFactor H Level Assay. Complement Factor H (FH; MW: 155 kDa) is an important fluid-phase and cell-surface regulator of alternative pathway (AP) activity. Patients with FH mutations or FH autoantibodies may have reduced plasma FH levels and/or function, and are at-risk to develop atypical hemolytic uremic syndrome or C3 glomerulopathy. WebApr 14, 2024 · Laboratory medicine is changing at a rapid pace. Our comprehensive range of programs constantly evolve to keep you in step with these changes so you have more time for what matters most—accuracy in the laboratory. Catalogs, Ordering, and Shipping Information SARS-CoV-2 Proficiency Testing Programs Quality Management Tools prof grethe